Izindaba

I-Tetrapeptide-3, eyaziwa nangokuthi i-AHK.Kuyi-peptide ende ye-amino acid engu-3, ​​ehlanganiswe ndawonye ukuze kwakhiwe i-peptide yokwenziwa.I-Tetrapeptide-3 itholakala esikhunjeni sawo wonke umuntu futhi ingasiza ukukhulisa impilo yesikhumba kanye namazinga omswakama.I-Tetrapeptide-3 iyingxenye yohlelo lokuzivikela lwemvelo lwesikhumba sakho, olwatholwa ososayensi ngo-2013 futhi manje ingesinye sezithako zokulwa nokuguga ezaziwa kakhulu emakethe.Imboni yezimonyo ibhekisela ku-AHK njengesici sokulungisa i-DNA kwezinye izimo.I-AHK iyisipho, kodwa hhayi ngaso sonke isikhathi, ihlanganiswe nethusi, yenzeI-AHK-Cu.

I-AHK itholakele, ocwaningweni lwezilwane kanye ne-in vitro, ukuze kusebenze ama-fibroblasts.Ama-Fibroblasts anesibopho sokukhiqiza okuningi kwe-extracellular matrix(amaprotheni angaphandle kwamaseli) okwenzeka esikhunjeni nakwezinye izicubu ezixhumeneyo (isb. amathambo, imisipha, njll.).I-Fibroblasts ibhekene ngokuyinhloko nokukhiqizwa kwe-collagen ne-elastin.I-Collage inika isikhumba amandla futhi iphinde isebenze ukuheha amanzi, yenza isikhumba sibe bushelelezi futhi sithandeke.I-Elastin inikeza isikhumba ikhono lokunwebeka futhi isiza ukuvimbela ukwakheka kwemigqa emihle nemibimbi.Ngokuhlangene, i-collagen ne-elastin zibandakanyeka kakhulu ekuvimbeleni ukuguga kwesikhumba, ngakho kokubili ubuningi kanye nekhwalithi lala maprotheni ehla njengoba sikhula.Ucwaningo lwemiphumela ye-AHK ku-collagen ne-elastin lubonisa ukuthi yandisa ukukhiqizwa kohlobo lwe-collagen l ngaphezu kwama-300%.

Omunye umphumela we-AHK usekukhiqizweni kwe-vascular endothelial growth factor kanye nokuguqula ukukhula kwe-beta-1.Amaseli e-Endothelial akha ingaphakathi lemithambo yegazi futhi anesibopho sezinyathelo eziningi zokuqala zokukhula kwemithambo yegazi Ukuguqula isici sokukhula kwe-beta-1 sikhulisa ukukhula kwamaseli, ukuhlukana, nokufa.Ngokwandisa ukugcinwa kwe-endothelial growth factor kanye nokunciphisa ukugcinwa kwe-beta-1 yesici sokukhula esishintshayo, i-AHK ingakhuthaza ukukhula kwemithambo yegazi, ikakhulukazi esikhumbeni.

Inzuzo ye-AHK

I-AHK isiza ukukhuthaza ukukhula kwe-collagen ne-elastin ukuqinisa ukwakheka kwesikhumba.Njengoba sikhula, i-epidermis (ungqimba lwangaphandle lwesikhumba esilubonayo) kanye ne-dermis (ungqimba olubamba i-collagen yethu ne-elastin) luqala ukuhlukana, olunganikeza ukubonakala kwesikhumba esincanyana kanye nemigqa egqamile nemibimbi.I-Tetrapeptide 3 isebenza ukuqinisa ukuxhumana phakathi kwalezi zingqimba ezimbili ukuze kuhambe kancane ukuguga.

I-AHK ingenye yama-peptide asebenza kahle kakhulu esikhumbeni angasetshenziswa ukwelapha izimo zesikhumba eziningi noma ukukhathazeka.Kuye kwafakazelwa ukuthi yelapha izinkinga eziningi ezihlanganisa ukuguga nemibimbi.

Kolunye ucwaningo lubonisa ukuthi i-AHK futhi ingavikela izimpande zezinwele ezikhona futhi isize nokukhula kabusha izinwele.