I-Oclacitinib maleate 1208319-27-0 Anti-inflammatory NSAID
Inkokhelo:T/T, L/C
Umsuka Womkhiqizo:China
Imbobo yokuthutha:Beijing/Shanghai/Hangzhou
I-oda (MOQ):10g
Isikhathi esiholayo:3 izinsuku zokusebenza
Amandla okukhiqiza:5kg/ngenyanga
Isimo sesitoreji:Igcinwe endaweni epholile, eyomile, izinga lokushisa legumbi.
Impahla yephakheji:ibhodlela
Usayizi wephakheji:10g/ibhodlela
Ulwazi lokuphepha:Akuzona izimpahla eziyingozi
Isingeniso
I-Oclacitinib, umuthi wezilwane osetshenziswa ekulawuleni i-atopic dermatitis kanye ne-pruritus kusuka ku-allergic dermatitis ezinjeni okungenani izinyanga eziyi-12 ubudala.Ngokwekhemikhali, iyi-synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor ekhetha ngokuqhathaniswa ku-JAK1.Ivimbela ukudluliselwa kwesignali lapho i-JAK icushiwe futhi ngaleyo ndlela isiza ukwehlisa ukubonakaliswa kwama-cytokines avuthayo.
I-Oclacitinib ibhalwe ukuthi yelapha i-atopic dermatitis kanye nokuluma (pruritus) okubangelwa ukungezwani nezinja, nakuba isetshenziselwe ukunciphisa ukulunywa kanye ne-dermatitis ebangelwa ukuhlasela kwamazeze.Ibhekwa njengesebenza kakhulu ezinjeni, futhi isungulwe njengephephile ukusetshenziswa okungenani isikhathi esifushane.
Ukucaciswa (izinga lasendlini)
| Into | Ukucaciswa |
| Ukubukeka | Okuqinile okumhlophe |
| HNMR | Ukuhambisana nesakhiwo |
| I-LC-MS | Ukuhambisana nesakhiwo |
| Ubumsulwa | ≥98% |
| Iphoyinti lokuncibilika | N/A |
