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Amashubhu eLabhorethri

Umkhiqizo

I-Rivaroxaban 366789-02-8 Uhlelo lwegazi luvikela i-Antithrombosis Isithombe Esifakiwe
  • I-Rivaroxaban 366789-02-8 Uhlelo lwegazi luvikela i-Antithrombosis

I-Rivaroxaban 366789-02-8 Uhlelo lwegazi luvikela i-Antithrombosis

Incazelo emfushane:

Omqondofana:5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide

Inombolo ye-CAS:366789-02-8

Ikhwalithi:EP

I-Molecular Formula:I-C19H18ClN3O5S

Isisindo Sefomula:435.88


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Inkokhelo:T/T, L/C
Umsuka Womkhiqizo:China
Imbobo yokuthutha:Beijing/Shanghai/Hangzhou
Amandla okukhiqiza:200kg/ngenyanga
I-oda(MOQ):25kg
Isikhathi esiholayo:3 Izinsuku Zokusebenza
Isimo sesitoreji:Igcinwe endaweni epholile, eyomile, izinga lokushisa legumbi.
Impahla yephakheji:isigubhu
Usayizi wephakheji:25kg/isigubhu
Ulwazi lokuphepha:Akuzona izimpahla eziyingozi

I-Rivaroxaban

Isingeniso

I-Rivaroxaban, imithi ye-anticoagulant (igazi elincane).Isetshenziswa kubantu abadala abane-nonvalvular atrial fibrillation (ngaphandle kwe-atrial fibrillation ngenxa ye-rheumatic valvular heart disease, kanye ne-atrial fibrillation ngemva kokushintshwa kwevalve yenhliziyo) ukunciphisa ingozi yokushaywa unhlangothi kanye ne-systemic embolism.
I-Rivaroxaban, isetshenziselwa ukwelapha nokuvimbela amahlule egazi.
I-Rivaroxaban, isetshenziselwa i-f ezigulini ezikhulile ezihlinzwa ngokukhethwa kwe-hip noma idolo ukuze kuvinjelwe i-venous thrombosis.

Ukucaciswa (EP)

Into

Ukucaciswa

Ukubukeka

Impushana emhlophe noma ephuzi

Ukuncibilika

Ayincibiliki emanzini, incibilika ngokukhululeka ku-DMSO, ayincibiliki ku-ethanol engena-hydrous namaheptane.

Ukuhlonza

IR: I-Spectrum kufanele ihambisane ne-WS
 

I-HPLC-RT yesampula ngaphansi kokuhlolwa kokuhlanzeka kwe-enantiometric kufanele ithobelane naleyo ye-WS.
Amanzi ≤0.5%

Umlotha we-sulphate

 ≤0.1%

Ukulahlekelwa ekomisweni

 ≤0.5%
Izinsimbi ezinzima ≤20ppm

I-enantionmer

 Ukungcola A: ≤0.4%

I-solvent eyinsalela

 I-Ethanol: ≤5000ppm

I-Ethyl acetate: ≤5000ppm

I-acetone: ≤5000ppm

N, N-Dimethylformamide: ≤880ppm

I-Methylene chloride: ≤600ppm

I-Benzene: ≤2ppm

Into ehlobene

 Ukungcola B: ≤0.10%

Ukungcola D: ≤0.10%

Ukungcola E: ≤0.10%

Ukungcola F: ≤0.10%

Ukungcola G: ≤0.10%

Ukungcola H: ≤0.10%

Ukungcola I: ≤0.10%

Ukungcola J: ≤0.10%

I-RVB-4-NJSH: ≤0.10%

I-RVB-ZA: ≤0.10%

I-RVB-BAM: ≤0.10%

I-RVB-ZC: ≤0.10%

I-RVB-HBY: ≤75ppm

Noma yikuphi okunye ukungcola okungaziwa: ≤0.10%

Ukungcola okuphelele: ≤0.3%

Ukusabalalisa usayizi we-particle

 D10:/

D50:/

I-D90:/
Isivivinyo

(into engenamanzi)

 98.0-102.0
  • Okwedlule:
  • Olandelayo:

    • imikhiqizo ehlobene