I-Ursodeoxycholic acid 128-13-2 Uhlelo lokugaya ukudla lwe-Cholagogic
Inkokhelo:T/T, L/C
Umsuka Womkhiqizo:China
Imbobo yokuthutha:Beijing/Shanghai/Hangzhou
Amandla okukhiqiza:2000kg/ngenyanga
I-oda(MOQ):25kg
Isikhathi esiholayo:3 Izinsuku Zokusebenza
Isimo sesitoreji:Igcinwe endaweni epholile, eyomile, izinga lokushisa legumbi.
Impahla yephakheji:isigubhu
Usayizi wephakheji:25kg/isigubhu
Ulwazi lokuphepha:Akuzona izimpahla eziyingozi
Isingeniso
I-Ursodeoxycholic acid (UDCA), eyaziwa nangokuthi i-ursodiol, i-bile acid yesibili, ekhiqizwa kubantu nezinye izinhlobo eziningi ezivela ku-metabolism ngamagciwane amathumbu.Ihlanganiswa esibindini kwezinye izinhlobo zezilwane, futhi yaqala ukukhonjwa ku-bile bile, okuwukususelwa kwegama layo elithi Ursus.Ngefomu elihlanjululwe, isetshenziselwe ukwelapha noma ukuvimbela izifo eziningana zesibindi noma i-bile ducts.
I-UDCA isetshenziswe njengokwelashwa kwezifo ze-gallstone (cholelithiasis) kanye nodaka lwe-biliary.I-UDCA isiza ukwehlisa ukugcwala kwe-cholesterol ku-bile futhi iholele ekuncibilikeni kancane kancane kwamatshe enyongo anothe nge-cholesterol.
I-UDCA ingase inikezwe ngemva kokuhlinzwa kwe-bariatric ukuvimbela i-cholelithiasis, evame ukwenzeka ngenxa yokuncipha kwesisindo esisheshayo okukhiqiza ukugcwala kwe-cholesterol ye-biliary kanye nezinguquko ze-biliary dyskinesia.
Ukucaciswa (EP10)
| Into | Ukucaciswa |
| Ukubukeka | Impushana emhlophe noma ecishe ibe mhlophe |
| Ukuncibilika | Ayincibiliki emanzini, incibilika ngokukhululeka ku-ethanol (96%), incibilika kancane ku-acetone, cishe ayincibiliki ku-methylene chloride. |
| Iphoyinti lokuncibilika | 202-204 ℃ |
| Ukuhlonza | I-spectrum ye-IR efanayo ne-ursodeoxycholic acid CRS |
| Indawo eyinhloko kuchromatogram etholwe ngesixazululo sokuhlola (b) iyafana ngokuma, umbala nosayizi nendawo eyinhloko kuchromatogram etholwe ngesixazululo sereferensi (a). | |
| Ukumiswa okutholiwe kuluhlaza okwesibhakabhaka. | |
| Ukujikeleza okuqondile kokubona | +58.0~+62.0° |
| Ukungcola C | I-Lithocholic acid ≤ 0.1% |
| Into ehlobene (HPLC) | ukungcola A: i-chenodeoxycholic acid ≤ 1.0% |
| ukungcola okungashiwongo ≤ 0.1% | |
| isamba ≤ 1.5% | |
| Izinsimbi ezinzima | I-ICH Q3D |
| Ukulahlekelwa ekomisweni | ≤ 1.0% |
| Umlotha one-sulphate | ≤ 0.1% |
| Isivivinyo | 99.0%~101% (Into eyomisiwe) |
| Izincibilikisi ezisele | I-acetone ≤ 5000 ppm I-Ethyl acetate ≤ 5000 ppm I-Isopropanol ≤ 5000 ppm I-Ethanol ≤ 5000 ppm |
| Ukuhlolwa kweMicrobiological | Isibalo se-aerobic microbial ≤ 10³CFU/g Isamba semvubelo nesikhunta sibala ≤ 10²CFU/g I-Escherichia coli: Ayikho ku-1 g I-Salmonella: Ayikho ku-10 g |
| Izakhiwo ezengeziwe | |
| Ukusabalalisa usayizi we-particle | 100% pass number 180 sieve (100% pass 80 mesh sieve) |
