I-Atipamezole HCL 104075-48-1 Antipyretic-analgesic
Inkokhelo:T/T, L/C
Umsuka Womkhiqizo:China
Imbobo yokuthutha:Beijing/Shanghai/Hangzhou
Amandla okukhiqiza:100kg/ngenyanga
I-oda(MOQ):25kg
Isikhathi esiholayo:3 Izinsuku Zokusebenza
Isimo sesitoreji:Igcinwe endaweni epholile, eyomile, izinga lokushisa legumbi
Impahla yephakheji:isigubhu
Usayizi wephakheji:25kg/isigubhu
Ulwazi lokuphepha:Akuzona izimpahla eziyingozi
Isingeniso
I-Atipamezole hydrochloride, igama lamakhemikhali: 4-(2-ethyl-2-indan) imidazole hydrochloride.I-Atipamezole hydrochloride ivimbela ngokuncintisana i-alpha 2 adrenergic receptors, futhi iyisivimbeli se-α2 se-adrenergic receptor, esivimbela ngokukhetha nangokuncintisana i-α2 adrenergic receptors.
Imiphumela yayo ye-pharmacological ukunciphisa ukuthuthumela, ukwehlisa umfutho wegazi, ukwandisa ukushaya kwenhliziyo kanye nezinga lokuphefumula, nokunciphisa imiphumela ye-analgesic ye-α2-adrenoceptor blockers, esetshenziswa kakhulu ekubuyiseleni i-anesthesia ngemva kokuhlinzwa ezilwaneni.
Ukucaciswa (izinga lasendlini)
| Into | Ukucaciswa |
| Ukubukeka | Okuqinile okumhlophe |
| Ukuhlonza | IR |
| Ukuhlonza ama-chloride | Ukuqhathaniswa nokuma |
| Iphoyinti lokuncibilika | 211℃-215℃ |
| Ukungcola okuphelele | ≤ 0.1% |
| Ukungakhethi komuntu ngamunye | ≤0.05% |
| Ukulahlekelwa ekomisweni | ≤0.05%2hrs ku-105℃ |
| Umlotha oxutshiwe | 0.05% ubuningi |
| Ph yesixazululo esijwayelekile | 5-6 |
| Isixazululo (1% ukuncibilika emanzini) | engenambala |
| Izinsimbi Ezisindayo eziphelele (Njenge-Pb Cd Cr Ni) | ≤20ppm |
| Izincibilikisi ezisele | I-acetone <5000ppm |
| I-methylbenzene<890ppm | |
| I-<720ppm | |
| I-Methanol <3000ppm | |
| I-Dichloromethane <600ppm | |
| I-Ethyl acetate<5000ppm | |
| I-N-hexane<290ppm | |
| I-Ethyl alcohol<5000ppm | |
| Ubumsulwa (HPLC) | ≥99% |
Ukucaciswa Ibanga lomjovo
| Into | Ukucaciswa |
| Ukubukeka | Impushana ephuzi ukuya kuwolintshi engenaphunga. |
| Ukuhlonza | IR, HPLC |
| Izinsalela ekushiseni | ≤0.5% |
| Izinto ezihlobene | |
| Ku-303nm | I-Amphotericin A ≤2.0% |
| Ukungcola komuntu ngamunye okungaziwa ≤1.0% | |
| kwe 383nm | I-Amphotericin X1 ≤4.0% |
| Ukungcola komuntu ngamunye okungaziwa ≤2.0% | |
| Ukungcola okuphelele | ≤15.0% |
| Izincibilikisi ezisele | I-acetone ≤0.5% |
| I-Methanol ≤0.3% | |
| Umkhawulo we-Microbiological | Isibalo se-Aerobic microbial ≤1000cfu/g |
| Izikhunta nama-yeasts ≤100cfu/g | |
| I-Escherichia coli Ayikho ku-1g | |
| Ama-bacterium endotoxins | <1.0EU/mg |
| Isivivinyo | ≥850 amphotericin B amayunithi/mg, abalwe ngesisekelo esomisiwe |
