I-Mirabegron 223673-61-8 Inhibitor isignali ye-Neuronal
Inkokhelo:T/T, L/C
Umsuka Womkhiqizo:China
Imbobo yokuthutha:Beijing/Shanghai/Hangzhou
Amandla okukhiqiza:100kg/ngenyanga
I-oda(MOQ):25kg
Isikhathi esiholayo:3 Izinsuku Zokusebenza
Isimo sesitoreji:Igcinwe endaweni epholile, eyomile, izinga lokushisa legumbi.
Impahla yephakheji:isigubhu
Usayizi wephakheji:25kg/isigubhu
Ulwazi lokuphepha:Akuzona izimpahla eziyingozi
Isingeniso
I-Mirabegron, iyi-beta-3 adrenergic receptor agonist, evuselela i-beta-3 adrenergic receptor futhi iphumuze imisipha ebushelelezi ye-detrusor, ngaleyo ndlela ikhulise umthamo wesinye futhi isetshenziselwe ukwelapha izimpawu zesinye esisebenza ngokweqile (OAB), njengokungakwazi ukuzithiba, ukuphuthuma, kanye nemvamisa.
Izinzuzo zayo zifana nemithi ye-antimuscarinic efana ne-solifenacin noma i-tolterodine.
Ukucaciswa (USP/EP)
| Into | Ukucaciswa |
| Ukubukeka | Impushana emhlophe iye emhlophe |
| Ukuhlonza | IR, HPLC |
| Okuqukethwe kwamanzi | I-NMT 0.5% |
| Izinsalela ekushiseni | I-NMT 0.1% |
| Insimbi enzima | I-NMT 20ppm |
| Okuqukethwe kwe-Palladium | I-NMT 20ppm |
| Isomer ye-Optical | I-NTM 0.5% |
| Into ehlobene | Z-168*: NMT 0.15% |
| SC03610*: NMT 0.15% | |
| Noma yikuphi okunye ukungcola okungaziwa: NMT 0.10% | |
| Ukungcola okuphelele: NMT 0.5% | |
| 2-(2-aminothianzol-4-yl) i-acetic acid | I-NMT 0.1% |
| I-solvent eyinsalela | I-Methanol: NMT 0.3% |
| I-Ethyl acetate: NMT 0.5% | |
| I-THF: NMT 0.072% | |
| I-Benzene: NMT 0.0002% | |
| I-Toluene: NMT 0.089% | |
| Isivivinyo | 98.0% - 102.0% |
| I-PSD | D (0.5): 10μm - 30μm |
| D (0.9): 20μm - 80μm |
